ViroMag R/L
ViroMag R/L Transduction Reagent is a magnetic nanoparticles formulation optimized for Retroviruses and Lentiviruses. Based on the Magnetofection™ technology, this reagent allows concentrating the complete applied dose of Retro/Lentiviral particles onto cells within minutes, inducing a significant improvement of virus infectivity with extremely low vector doses. Due to its specific properties, ViroMag R/L is ideal to infect non permissive cells. This reagent demonstrates an exceptionally high efficiency to promote, control and assist viral transductions in a so that no molecular biology processes or biochemical modifications are required.
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Increase transduction efficiency
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Accelerate the transduction process
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Efficient for hard-to-infect and non-permissive cells
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Concentrate the viral dose onto the cells
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Suitable for all type of Retro/Lentivirus
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Synchronise cells adsorption/infection without modifications of the viruses
ViroMag RL can also be used for Genome Edition using the CRISPR-Cas9 system (see Application Note in Technical Resources). It is design for the transfection of a viral particle solution composed by either one viral vector or vectors encoding cas9 and sgRNA.
"Use of ViroMag R/L to knock down a gene by CRISPR/Cas9-guided genome editing with Lentivirus in THP-1 cells"
Safronova A et al, Nature Immuno. 2018
Safronova A et al, Nature Immuno. 2018
"The magnetofection beads have been a game-changer for the transduction efficiency of our lentiviruses. We are using very hard to transduce B-lymphoblastomas that grow in suspension and viral concentration using filtering in conjunction with ViroMag R/L has brought our efficiency up from about 2% to 70-80%. High transduction efficiency on mammary epithelial organoids in suspension"
ViroMag R/L transduction reagent:
Sizes:
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100 µL 30-500 transductions in 96-well plate
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200 µL 60-1,000 transductions in 96 well plate
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1 mL 300-5,000 transductions in 96-well plate
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#KC30700: ViroMag R/L Starting Kit with Super Magnetic plate + 200µL of ViroMag R/L
- #KC30796 : ViroMag R/L Starting Kit with plate 96 magnets + 200µL of ViroMag R/L
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#KC30600: ViroMag Triple Starting Kit with Super Magnetic plate + 100 µL of ViroMag, AdenoMag, ViroMag RL
- #KC30696 : ViroMag Triple Starting Kit with plate 96 magnets + 100 µL of ViroMag, AdenoMag, ViroMag RL
Storage: +4°C
Shipping Conditions: Room Temperature
- This reagent needs to be used with a magnetic plate
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| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| RL40100 |
100 µL
|
$146.00
|
|
| RL40200 |
200 µL
|
$267.00
|
|
| RL41000 |
1 mL
|
$1,059.00
|
|
| KC30700 |
ViroMag R/L Starting Kit
|
$801.00
|
|
| KC30796 |
ViroMag R/L Starting kit plate 96 magnets
|
$631.00
|
|
| KC30600 |
ViroMag Triple Starting Kit
|
$691.00
|
|
| KC30696 |
ViroMag Triple Starting Kit with plate 96 magnets
|
$651.00
|
|
RL40100
100 µL
$146.00
RL40200
200 µL
$267.00
RL41000
1 mL
$1,059.00
KC30700
ViroMag R/L Starting Kit
$801.00
KC30796
ViroMag R/L Starting kit plate 96 magnets
$631.00
KC30600
ViroMag Triple Starting Kit
$691.00
KC30696
ViroMag Triple Starting Kit with plate 96 magnets
$651.00
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