mRNAs
Optimized and Stabilized mRNAs
OZ Biosciences offers mRNAs that mimic fully processed mature mRNAs. These mRNAs are stabilized with 5’ Cap 1 structure and 3’ poly(A) tail and are optimized to yield improved stability & performance. They are modified with 5-methoxyuridine (5moU replaces U) or N1-methyl-pseudouridine (N1-mψ) to reduce innate immune responses. We also offer unmodified mRNAs.
7 categories of ready-to-use mRNAs
- Reporter gene mRNAs: ideal controls to study transfection efficiency.
- Genome editing mRNAs: ideal for Genome editing.
- Vaccine mRNAs: ideal as controls for immunization or vaccine studies.
- Gene Replacement mRNAs: EPO mRNA
- Fluorescent mRNAs: Cy5 F-Luc mRNA, Cy5 GFP mRNA
- Interleukin mRNA: H IL-2 mRNA
- Transcription Factor mRNA: c-Myc mRNA
Custom mRNA Synthesis Service
With over 15 years of nucleic acid delivery expertise, OZ Biosciences is confident in providing you with the best-in-class service for the production of high quality mRNAs.
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We are able to synthesis custom mRNAs at microgram to multigram scales, from a few hundred up to several thousand bases, with a wide variety of modifications including 5’ terminal modifications with cap, internal modification such as 5-methoxyuridine (other modified nucleotides are available) and 3’ modification such as poly-A tail. fluorescent labeling with Cy5, Cy3 or other options is available. |
Production Process
Spike DELTA mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
EPO mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
Spike Omicron mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
Spike SARS CoV-2 mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
R-Luc mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
β-Gal mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
mCherry mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
OVA mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
F-Luc mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
Tomato mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
GFP mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
CRE mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
Cas9 mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
Cy5 GFP mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
Cy5 F-Luc mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
Cas13d mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
HA(-TMD)-H1N1 mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
h IL-2 mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
N SARS-Cov-2 mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
HA-H3N2 mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
IVT Kit
Maximize your research with our...
Poly(A) Kit
Enhance your research with our Poly(A) Tailing Kit. Designed for the...
Capping Kit
Enhance the stability and translation of your mRNA with our in vitro...
Cy3 GFP mRNA
Cy3 F-Luc mRNA
Alexa488 F-Luc mRNA
c-Myc mRNA
h Sox2 mRNA
mRNA encoding human Sox2 transcription factor
HA(FL)-H1N1 mRNA
Unmodified / 5-methoxyuridine / N1-methylpseudouridine
saRNA GFP
Unmodified / m5C
saRNA Luc
Unmodified / m5C