CRE mRNA
CRE mRNA has been designed to produce high expression level of CRE recombinase fused to a nuclear localization sequence (NLS).
OZ Biosciences mRNAs are produced by in vitro transcription and stabilized at the 5’ end by modified nucleotides capping (Cap1). These mature mRNAs contain a poly(A) tail at the 3’ end and are also optimized to yield improved stability and performance.
CRE mRNAs:
- #MRNA33 does not bear any additional nucleotide modifications.
- #MRNA32 is modified with 5-methoxyuridine (5moU) to reduce innate immune responses.
- #MRNA26 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.
Quality Control
Items | Specification | Standard QC | Superior Grade QC* |
---|---|---|---|
Appearance | Clear | ✓ | ✓ |
Integrity | One peak, right size | ✓ | ✓ |
One peak, right size | ✓ | ✓ | |
Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
A260/280 | >1.8 for Unmod, >1.7 for modified | ✓ | ✓ |
Sterility | Absence of growth after 14 days | ✓ | ✓ |
Endotoxin | <0.5 EU/mL | ✓ | |
dsRNA | <0.5% | ✓ | |
Fonctionality | protein expression after transfection | ✓ | ✓ |
* Contact us to get a quote.
Size: 20 µg or 100µg
For bulk, please contact us: order@ozbiosciences.com
Storage: -80°C
Shipping: Dry ice (fee included in shipping cost)
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Catalog number | Unit Size | Price excl tax | Quantity / Buy |
MRNA33-20 |
CRE mRNA Unmodified 20 µg
|
$176.00
|
|
MRNA33-100 |
CRE mRNA Unmodified 100 µg
|
$282.00
|
|
MRNA33-1000 |
CRE mRNA Unmodified 1 mg
|
$1,556.00
|
|
MRNA32-20 |
CRE mRNA (5moU) 20 µg
|
$184.00
|
|
MRNA32-100 |
CRE mRNA (5moU) 100 µg
|
$350.00
|
|
MRNA32-1000 |
CRE mRNA (5moU) 1 mg
|
$1,878.00
|
|
MRNA26-20 |
CRE mRNA (N1-mψ) 20 µg
|
$206.00
|
|
MRNA26-100 |
CRE mRNA (N1-mψ) 100 µg
|
$372.00
|
|
MRNA26-1000 |
CRE mRNA (N1-mψ) 1 mg
|
$1,901.00
|
|
Citation database
NAME | MOLECULE VECTOR | PRODUCT | REFERENCE | |
all cells | 0 | Cre mRNA | Tsujimura T. bioRxiv 2019. doi: https://doi.org/10.1101/534073 |
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