Cas9 mRNA
Cas9 mRNA has been designed to produce high expression level of wild-type endonuclease CRISPR associated (Cas) protein 9.
OZ Biosciences mRNAs are produced by in vitro transcription and stabilized at the 5’ end by modified nucleotides capping (Cap1). These mature mRNAs contain a poly(A) tail at the 3’ end and are also optimized to yield improved stability and performance.
Cas9 mRNAs:
- #MRNA30 does not bear any additional nucleotide modifications.
- #MRNA31 is modified with 5-methoxyuridine (5moU) to reduce innate immune responses.
- #MRNA25 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.
Quality Control
| Items | Specification | Standard QC | Superior Grade QC* |
|---|---|---|---|
| Appearance | Clear | ✓ | ✓ |
| Integrity | One peak, right size | ✓ | ✓ |
| One peak, right size | ✓ | ✓ | |
| Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
| A260/280 | >1.8 for Unmod, >1.7 for modified | ✓ | ✓ |
| Sterility | Absence of growth after 14 days | ✓ | ✓ |
| Endotoxin | <0.5 EU/mL | ✓ | |
| dsRNA | <0.5% | ✓ | |
| Fonctionality | protein expression after transfection | ✓ | ✓ |
* Contact us to get a quote.
Size: 20 µg, 100µg and 1 mg
For bulk, please contact us: order@ozbiosciences.com
Storage: -80°C
Shipping : Dry ice (fee included in shipping cost)
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| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA30-20 |
Cas9 mRNA 20 µg
|
$185.00
|
|
| MRNA30-100 |
Cas9 mRNA 100 µg
|
$351.00
|
|
| MRNA30-1000 |
Cas9 mRNA 1 mg
|
$1,887.00
|
|
| MRNA31-20 |
Cas9 mRNA (5moU) 20 µg
|
$184.00
|
|
| MRNA31-100 |
Cas9 mRNA (5moU) 100 µg
|
$415.00
|
|
| MRNA31-1000 |
Cas9 mRNA (5moU) 1 mg
|
$2,223.00
|
|
| MRNA25-20 |
Cas9 mRNA (N1-mψ) 20 µg
|
$206.00
|
|
| MRNA25-100 |
Cas9 mRNA (N1-mψ) 100 µg
|
$436.00
|
|
| MRNA25-1000 |
Cas9 mRNA (N1-mψ) 1 mg
|
$2,244.00
|
|
MRNA30-20
Cas9 mRNA 20 µg
$185.00
MRNA30-100
Cas9 mRNA 100 µg
$351.00
MRNA30-1000
Cas9 mRNA 1 mg
$1,887.00
MRNA31-20
Cas9 mRNA (5moU) 20 µg
$184.00
MRNA31-100
Cas9 mRNA (5moU) 100 µg
$415.00
MRNA31-1000
Cas9 mRNA (5moU) 1 mg
$2,223.00
MRNA25-20
Cas9 mRNA (N1-mψ) 20 µg
$206.00
MRNA25-100
Cas9 mRNA (N1-mψ) 100 µg
$436.00
MRNA25-1000
Cas9 mRNA (N1-mψ) 1 mg
$2,244.00
Citation database
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Unmodified / 5-methoxyuridine / N1-methylpseudouridine