Blog
-
Lipid Nanoparticle Development for Bivalent mRNA Vaccine
Published : 06/25/2025Authors: Jiin Felgner et al. Source: npj Vaccines. "mRNA vaccines represent a promising alternative to conventional vaccines, as demonstrated by the rapid deployment of mRNA vaccines...
-
T cell receptor mimic CAR T cells targeting cathepsin G signal peptide
Published : 06/18/2025Authors: Yan, J. et al. Source: Leukemia. "There has been a been a paucity of immunotherapy targets in myeloid malignancies. We identified the HLA-A2 (A2)...
-
HYPE-293 is now available in Superior Grade quality control
Published : 06/11/2025We're pleased to announce the development of a new HYPE-293 Superior Grade. Identic to HYPE-293 with extensive quality controls for preclinical trial use.
-
Impact of pre-existing anti-polyethylene glycol (PEG) IgM on biodistribution
Published : 06/04/2025Authors: Shunji Abe et al. Source: Journal of Controlled Release. "With the approval of mRNA vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), lipid nanoparticles (LNP)...
-
siNPAIN project: bi-annual progress meeting at i3S, in Porto
Published : 05/27/2025We're now at month 36 of this 54-month European project, and we’re proud to lead Work Package 1.
-
New kit for the detection of Double-stranded RNA
Published : 05/21/2025We are pleased to announce that we are launching a new kit for the detection of Double-stranded RNA.
-
New enzyme for low dsRNA in our mRNAs!
Published : 05/14/2025As part of our continuous quality improvement, we have selected a new generation of RNA polymerase that reduces dsRNA during IVT.
-
Magnetic-Guided Delivery of Antisense Oligonucleotides for Targeted Transduction
Published : 05/09/2025Authors: Xiuhong Ye et al. Source: Adv. Sci. 2025. "Antisense oligonucleotide (ASO) therapy holds promise in gene therapy but faces challenges due to poor delivery efficiency...