Blog
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A multichaperone condensate enhances protein folding in the endoplasmic reticulu
Published : 08/27/2025Authors: Leder, A., Mas, G., Szentgyörgyi, V. et al. Source: Nat Cell Biol. They discovered that the ER protein PDIA6 forms dynamic, calcium-dependent multichaperone condensates...
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Lipid Nanoparticles (LNPs): A complete guide for researchers
Published : 08/21/2025Lipid nanoparticles (LNPs) have become essential tools in nucleic acid delivery, gene therapy, and mRNA vaccines. This guide covers their production and experimental performance.
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Concentration-dependent anti-inflammatory effects of BHB on microglia
Published : 08/13/2025Authors: Garcia Chase et al. Source: Frontiers in Aging. They uncovered key mechanisms behind the ketogenic diet's benefits for memory and longevity...
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A comparative study of cationic lipid-enriched LNPs for mRNA vaccine delivery
Published : 08/06/2025Authors: Burcu Binici et al. Source: International Journal of Pharmaceutics. "Lipid nanoparticles (LNPs) play a central role in mRNA vaccine delivery...
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A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies
Published : 07/30/2025Authors: Xun Chen et al. Source: Sci. Adv. Focusing on the evolutionarily young LTR subfamilies known as MER11A/B/C, they revealed the presence of four “new subfamilies,”...
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Live-cell magnetic manipulation of endosomes’ effect on actin protrusions
Published : 07/23/2025Authors: Jakub Gemperle et al. Source: Sci. Adv. Scientists utilized an innovative magnetogenetic approach to precisely control Rab25 endosomes,...
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Aberrant phase separation of two PKA RIβ neurological disorder mutants
Published : 07/16/2025Authors: Pool, Emily H. et al. Source: Cell Reports. "Spatiotemporal regulation of key-node signaling molecules, such as 3′,5′-cyclic adenosine monophosphate...
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mRNA and LNPs: A guide to fluorescent labeling to enhance research
Published : 07/11/2025Fluorescent labeling is a commonly used technique in mRNA and LNP research. It allows for easy visualization and tracking of these molecules in cells and tissues.