Blog
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DART project: novel mRNA delivery systems for vaccines
Published : 10/19/2026OZ Biosciences participates in the DART project, developing ionizable polymer-based mRNA delivery systems as an alternative to LNPs for vaccines.
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Eurostars Project CAPSULIX: mRNA and LNPs for engineered cell therapy
Published : 10/14/2026The consortium composed of OZ Biosciences, ExploRNA, and Miltenyi Biotec will deliver a novel cell-based therapy manufacturing platform to treat cancer with CAR expressing T cells.
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Activity-dependent 5′tRF GluCTC modulates neuronal networks in hiPSC neurons
Published : 10/07/2026Authors: Stewart, R. et al. Source: Cell Death Dis. They investigated the activity-dependent generation and extracellular release of 5′tRF GluCTC in hiPSC-derived cortical neurons...
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Small-Molecule-Mediated Depletion of the DYRK1B Protein Scaffold
Published : 09/30/2026Authors: Miriam Ems, et al. Source: ACS Pharmacol. Transl. Sci. They identified LCTB-92, a small molecule from the leucettinib class of DYRK inhibitors...
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LNP-mediated mRNA delivery in human PBMC: T cell-targeted transfection
Published : 09/24/2026Application note: transfection efficiency, cell-type tropism and viability of a new ionizable lipid LNP formulation in human PBMCs, with focus on T cells.
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Geneformer-guided multiomics identifies Pbx1 as a network hub of HSC aging
Published : 09/16/2026Authors: Hiroshi Kobayashi et al. Source: Science Advances. They integrated deep learning foundation models with transcriptomic and epigenetic profiling to...
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Our cationic poloxamers patent is now granted in Australia
Published : 09/09/2026Patent No. AU2020314617, “CATIONIC POLOXAMERS AND THEIR USE IN TRANSDUCTION,” covers our method for synthetically modifying poloxamers to confer additional biological properties...
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Caspase-3 regulates RNA splicing and mitochondrial dynamics in microglia
Published : 09/02/2026Authors: Medina-Guzmán, R., et al. Source: Cell Death Dis. They showed that basal caspase-3 activity regulates RNA splicing in microglia, and its deficiency in a Parkinson's disease...