Blog
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Why choose mRNAs over pDNA?
Published : 09/24/2025Discover why mRNA is safer and more efficient than plasmid DNA: faster protein expression, no genomic integration, and promoter-independent benefits.
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Cholesterol in mRNA-Lipid Nanoparticles can be Replaced with the Synthetic MMG-1
Published : 09/17/2025Authors: A. G. Lokras, et al. Source: Adv. Funct. Mater. (2025). They demonstrated that replacing cholesterol in mRNA-Lipid Nanoparticles (LNPs)...
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Uukuniemi virus infection remodels the RNA-binding proteome in tick cells
Published : 09/10/2025Authors: Wilson A, Kamel W, Davies K, De Laurent ZR, Arif R, et al. Source: PLOS Pathogens. They conducted the first comprehensive analysis of protein-RNA interactions...
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Protocadherin γC4 Promotes Neuronal Survival in the Mouse Retina
Published : 09/03/2025Authors: McLeod, C.M., Lanthier, H.G., Nitschke, G.R. et al. Source: Mol Neurobiol (2025). They investigated the complex regulation of developmental neuronal apoptosis...
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A multichaperone condensate enhances protein folding in the endoplasmic reticulu
Published : 08/27/2025Authors: Leder, A., Mas, G., Szentgyörgyi, V. et al. Source: Nat Cell Biol. They discovered that the ER protein PDIA6 forms dynamic, calcium-dependent multichaperone condensates...
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Lipid Nanoparticles (LNPs): A complete guide for researchers
Published : 08/21/2025Lipid nanoparticles (LNPs) have become essential tools in nucleic acid delivery, gene therapy, and mRNA vaccines. This guide covers their production and experimental performance.
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Concentration-dependent anti-inflammatory effects of BHB on microglia
Published : 08/13/2025Authors: Garcia Chase et al. Source: Frontiers in Aging. They uncovered key mechanisms behind the ketogenic diet's benefits for memory and longevity...
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A comparative study of cationic lipid-enriched LNPs for mRNA vaccine delivery
Published : 08/06/2025Authors: Burcu Binici et al. Source: International Journal of Pharmaceutics. "Lipid nanoparticles (LNPs) play a central role in mRNA vaccine delivery...