Blog
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Enhancing transduction efficiency of lentiviral vectors in CAR-T cell therapy
Published : 03/19/2026Authors: Ferreira R et al. Source: Front. Med. The stepwise optimization developed in this study brought transduction efficiency of the anti-FITC-CAR construct from an average of ~1% to ~50%
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An mRNA-encoded scFv antibody targeting the helix-α3 of HPV18 E7 oncoprotein
Published : 03/11/2026Authors: Feng Han et al. Source: mBio. They identified a novel antiviral target on the HPV18 E7 oncoprotein and demonstrated...
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Discovery of a selective ERAP1 inhibitor for Hedgehog-dependent cancer treatment
Published : 02/26/2026Authors: Bufalieri, Francesca et al. Source: Molecular Therapy. They identified Canthin-6-one (N1) as a selective inhibitor of ERAP1...
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Longitudinal Analysis of Male Fertility Using an Acr-Luc Knock-In Mouse Model
Published : 02/12/2026Authors: H. Fukunaga, R. Seino, Y. Matsuya, et al. Source: MedComm. They successfully established a novel Acr-Luc knock-in mouse model that enables longitudinal...
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Scientific advances in oncology: 2025 studies using OZ Biosciences tools
Published : 01/28/2026World Cancer Day is a good reminder of the research happening globally to advance cancer treatment. We've put together a brief selection of 2025 studies...
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Bibliography Highlights 2025
Published : 01/21/2026Discover a 2025 summary of publications featuring OZ Biosciences delivery tools, covering widely used nucleic acid formats, delivery strategies and biological models.
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17,18-epoxyeicosatetraenoic acid ameliorates mRNA-LNP–induced local inflammation
Published : 01/14/2026Authors: Iemitsu, Keigo et al. Source: Journal of Lipid Research. They demonstrated that lipid nanoparticles (LNPs), the crucial delivery platform for mRNA vaccines,...
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Systematic Evaluation of GAPs and GEFs Identifies a Targetable Dependency
Published : 01/07/2026Authors: Pu Zhang, Zhendong Cao et al. Source: Cancer Discov. They utilized unbiased CRISPR-based functional genomics screens in Acute Myeloid Leukemia (AML)...