Blog
-
SMURF1 and SMURF2 target GLI1 for ubiquitination and degradation
Published : 01/08/2025Authors: Fabio Bordin, Gloria Terriaca et al. Source: Cell Death Discovery The transcription factor GLI1 is the main and final effector of the Hedgehog signaling pathway, which is involved in [...]
-
Periodic ER-PM junctions enable long-range Ca2+ signaling
Published : 01/03/2025Authors: Lorena Benedetti et al. Source: Cell We are thrilled to share insights from a groundbreaking study entitled "Periodic ER-plasma membrane junctions support long-range Ca2+ signal [...]
-
Challenges in AAV-Based Retinal Gene Therapies
Published : 12/18/2024Authors: Oliver Siontas and Seungkuk Ahn. Source: Journal of Clinical Medicine We are thrilled to share insights from a new study titled "Challenges in AAV-Based Retinal Gene Therapies and th [...]
-
Anti-SARS-CoV-2 serology and neutralizing antibodies against Omicron variants
Published : 12/10/2024Authors: Léa Dépéry et al. Source: ASM Journals We are thrilled to share insights from a recent study titled "Anti-SARS-CoV-2 serology based on ancestral RBD antigens does not correlate with [...]
-
New insights into PPP2R2B variants in neurodevelopmental syndrome
Published : 12/05/2024Authors: Priyanka Sandal, Chian Ju Jong et al. Source: Human Molecular Genetics We are thrilled to share insights from a recent study titled "De novo missense variants in the PP2A regulatory [...]
-
Gene therapy improves outcomes in a mouse model of multiple sulfatase deficiency
Published : 04/08/2024Multiple Sulfatase Deficiency (MSD) is a severe lysosomal storage disease caused by pathogenic variants in the SUMF1 gene.
-
Phenotypic profiling of solute carriers characterizes serine transport in cancer
Published : 02/01/2024Our product was purchase by a renowned group of researchers in the field of biosciences.
-
New publication: Local magnetic delivery of adeno-associated virus AAV2
Published : 03/17/2022Use of Mag4C-Ad to capture and magnetically locally deliver adeno-associated virus AAV2 in vivo. Goal: gene therapy into the rat inner ear via minimally invasive magnetic targeting.