Blog
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Discovery of a selective ERAP1 inhibitor for Hedgehog-dependent cancer treatment
Published : 02/26/2026Authors: Bufalieri, Francesca et al. Source: Molecular Therapy. They identified Canthin-6-one (N1) as a selective inhibitor of ERAP1...
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Longitudinal Analysis of Male Fertility Using an Acr-Luc Knock-In Mouse Model
Published : 02/12/2026Authors: H. Fukunaga, R. Seino, Y. Matsuya, et al. Source: MedComm. They successfully established a novel Acr-Luc knock-in mouse model that enables longitudinal...
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Scientific advances in oncology: 2025 studies using OZ Biosciences tools
Published : 01/28/2026World Cancer Day is a good reminder of the research happening globally to advance cancer treatment. We've put together a brief selection of 2025 studies...
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Bibliography Highlights 2025
Published : 01/21/2026Discover a 2025 summary of publications featuring OZ Biosciences delivery tools, covering widely used nucleic acid formats, delivery strategies and biological models.
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17,18-epoxyeicosatetraenoic acid ameliorates mRNA-LNP–induced local inflammation
Published : 01/14/2026Authors: Iemitsu, Keigo et al. Source: Journal of Lipid Research. They demonstrated that lipid nanoparticles (LNPs), the crucial delivery platform for mRNA vaccines,...
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Systematic Evaluation of GAPs and GEFs Identifies a Targetable Dependency
Published : 01/07/2026Authors: Pu Zhang, Zhendong Cao et al. Source: Cancer Discov. They utilized unbiased CRISPR-based functional genomics screens in Acute Myeloid Leukemia (AML)...
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Meningococci drive host membrane tubulation to recruit their signaling receptors
Published : 12/31/2025Authors: Laurent-Granger, A., Sollier, K., Saubamea, B. et al. Source: Nat Commun. They uncovered a crucial survival strategy utilized by Neisseria meningitidis...
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RNA innate immunity constitutes a barrier for interspecies chimerism
Published : 12/17/2025Authors: Hu, Yingying et al. Source: Cell. They uncovered a crucial barrier to generating interspecies chimeras: the competitive elimination of human pluripotent stem cells...