HA(-TMD)-H1N1 mRNA
HA(-TMD)-H1N1 mRNA has been designed to produce high expression level of the (HA) hemagglutinin surface glycoproteins of H1N1 subtype of Influenza A virus.
OZB mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
HA-H1N1 mRNAs:
- #MRNA46 does not bear any additional nucleotide modifications. Molecular weight: 583820 g/mol.
- #MRNA47 is modified with 5-methoxyuridine (5moU) to reduce innate immune response. Molecular weight: 590840 g/mol.
- #MRNA48 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response. Molecular weight: 587330 g/mol.
⚠️ This mRNA encodes for the Hemagglutinin protein of the H1N1 flu virus without its transmembrane domain.
Quality Control
Items | Specification | Standard QC | Superior Grade QC* |
---|---|---|---|
Appearance | Clear | ✓ | ✓ |
Integrity | One peak, right size | ✓ | ✓ |
One peak, right size | ✓ | ✓ | |
Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
A260/280 | >1.8 for Unmod, >1.7 for modified | ✓ | ✓ |
Sterility | Absence of growth after 14 days | ✓ | ✓ |
Endotoxin | <0.5 EU/mL | ✓ | |
dsRNA | <0.5% | ✓ | |
Fonctionality | protein expression after transfection | ✓ |
* Contact us to get a quote.
mRNA length: 1804 nucleotides.
Size: 20 µg, 100µg or 1 mg.
For bulk, please contact us: order@ozbiosciences.com
Storage: -80°C
Shipping : Dry ice (fee included in shipping cost)
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Catalog number | Unit Size | Price excl tax | Quantity / Buy |
MRNA46-20 |
Unmodified HA-H1N1 mRNA 20 µg
|
$176.00
|
|
MRNA46-100 |
Unmodified HA-H1N1 mRNA 100 µg
|
$282.00
|
|
MRNA46-1000 |
Unmodified HA-H1N1 mRNA 1 mg
|
$1,556.00
|
|
MRNA47-20 |
HA-H1N1 mRNA (5moU) 20 µg
|
$184.00
|
|
MRNA47-100 |
HA-H1N1 mRNA (5moU) 100 µg
|
$378.00
|
|
MRNA47-1000 |
HA-H1N1 mRNA (5moU) 1 mg
|
$1,878.00
|
|
MRNA48-20 |
HA-H1N1 mRNA (N1-mψ) 20 µg
|
$206.00
|
|
MRNA48-100 |
HA-H1N1 mRNA (N1-mψ) 100 µg
|
$372.00
|
|
MRNA48-1000 |
HA-H1N1 mRNA (N1-mψ) 1 mg
|
$1,901.00
|
|
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