Spike SARS CoV-2 mRNA
Spike SARS CoV-2 (E484K; N501Y) mRNAs have been designed to produce high expression level of spike protein of SARS-CoV-2 virus.
OZB mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
Spike protein of SARS-CoV-2 virus mRNA (ref# MRNA34) does not bear any additional nucleotide modifications while (ref# MRNA35) is modified with 5-methoxyuridine (5moU) to reduce innate immune responses.
We suggest using the transfection reagents RmesFect™ (#RM21000) or RmesFect™ Stem (#RS31000) in order to reach high transfection efficiency and optimum protein expression level.
Quality Control
| Items | Specification | Standard QC | Superior Grade QC* |
|---|---|---|---|
| Appearance | Clear | ✓ | ✓ |
| Integrity | Agarose gel mobility and fragment analyzer | ✓ | ✓ |
| Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
| A260/280 | >1.8 for Unmod, >1.7 for modified | ✓ | ✓ |
| Sterility | Absence of growth | ✓ | ✓ |
| Endotoxin | <0.5 EU/mL | ✓ | |
| dsRNA | <0.5% | ✓ | |
| Functionality | protein expression after transfection | ✓ | ✓ |
* Contact us to get a quote.
Size: 20 µg, 100µg or 1 mg.
For bulk, please contact us: order@ozbiosciences.com
Storage: -80°C
Shipping: Dry ice (fee included in shipping cost)
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| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA 35-20 |
Spike SARS-CoV-2 mRNA (5moU) 20 µg
|
$184.00
|
|
| MRNA 35-100 |
Spike SARS-CoV-2 mRNA (5moU) 100 µg
|
$415.00
|
|
| MRNA 35-1000 |
Spike SARS-CoV-2 mRNA (5moU) 1 mg
|
$2,223.00
|
|
| MRNA 34-20 |
Unmodified Spike SARS-CoV-2 mRNA 20 µg
|
$185.00
|
|
| MRNA 34-100 |
Unmodified Spike SARS-CoV-2 mRNA 100 µg
|
$351.00
|
|
| MRNA 34-1000 |
Unmodified Spike SARS-CoV-2 mRNA 1 mg
|
$1,887.00
|
|
| MRNA43-20 |
Spike SARS-CoV-2 mRNA (N1-mψ) 20 µg
|
$206.00
|
|
| MRNA43-100 |
Spike SARS-CoV-2 mRNA (N1-mψ) 100 µg
|
$436.00
|
|
| MRNA43-1000 |
Spike SARS-CoV-2 mRNA (N1-mψ) 1 mg
|
$2,244.00
|
|
MRNA 35-20
Spike SARS-CoV-2 mRNA (5moU) 20 µg
$184.00
MRNA 35-100
Spike SARS-CoV-2 mRNA (5moU) 100 µg
$415.00
MRNA 35-1000
Spike SARS-CoV-2 mRNA (5moU) 1 mg
$2,223.00
MRNA 34-20
Unmodified Spike SARS-CoV-2 mRNA 20 µg
$185.00
MRNA 34-100
Unmodified Spike SARS-CoV-2 mRNA 100 µg
$351.00
MRNA 34-1000
Unmodified Spike SARS-CoV-2 mRNA 1 mg
$1,887.00
MRNA43-20
Spike SARS-CoV-2 mRNA (N1-mψ) 20 µg
$206.00
MRNA43-100
Spike SARS-CoV-2 mRNA (N1-mψ) 100 µg
$436.00
MRNA43-1000
Spike SARS-CoV-2 mRNA (N1-mψ) 1 mg
$2,244.00
Citation database
| NAME | MOLECULE VECTOR | PRODUCT | REFERENCE | |
| all cells | 0 | Spike SARS CoV-2 mRNA | Felgner J. NPJ Vaccines. 2025 Jun 11;10(1):123. | |
| all cells | 0 | Spike SARS CoV-2 mRNA | Abe S. J Control Release 2025 May 9:383:113821. | |
| all cells | 0 | Spike SARS CoV-2 mRNA | Bakos T. bioRxiv. 2024 doi.org/10.1101/2024.01.12.575122 |
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