Spike SARS CoV-2 mRNA
Spike SARS CoV-2 (E484K; N501Y) mRNAs have been designed to produce high expression level of spike protein of SARS-CoV-2 virus.
OZB mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
Spike protein of SARS-CoV-2 virus mRNA (ref# MRNA34) does not bear any additional nucleotide modifications while (ref# MRNA35) is modified with 5-methoxyuridine (5moU) to reduce innate immune responses.
We suggest using the transfection reagents RmesFect™ (#RM21000) or RmesFect™ Stem (#RS31000) in order to reach high transfection efficiency and optimum protein expression level.
Quality Control
Items
|
specification
|
Standard QC |
Superior Grade QC* |
Appearance |
clear |
✓ |
✓ |
Integrity |
one peak, right size |
✓ |
✓ |
one peak, right size |
✓ |
✓ |
|
Concentration |
1mg/ml +/- 5% |
✓ |
✓ |
A260/280 |
>1,8 for Unmod , >1,7 for modified |
✓ |
✓ |
Sterility |
absence of growth after 14 days |
✓ |
✓ |
Endotoxin |
<0,5 EU/ml |
|
✓ |
dsRNA |
<0,05% |
|
✓ |
Fonctionality |
protein expression after transfection |
✓ |
✓ |
Fluorophore concentration |
>/= 10pmol/µl |
✓ |
✓ |
* Contact us to get a quote.
Size: 20 µg, 100µg or 1 mg.
For bulk, please contact us: order@ozbiosciences.com
Storage: -80°C
Shipping: Dry ice (fee included in shipping cost)
Please log in or register to see the prices for your country
Catalog number | Unit Size | Price excl tax | Quantity / Buy |
MRNA 35-20 |
Spike SARS-CoV-2 mRNA (5moU) 20 µg
|
$184.00
|
|
MRNA 35-100 |
Spike SARS-CoV-2 mRNA (5moU) 100 µg
|
$415.00
|
|
MRNA 35-1000 |
Spike SARS-CoV-2 mRNA (5moU) 1 mg
|
$2,223.00
|
|
MRNA 34-20 |
Unmodified Spike SARS-CoV-2 mRNA 20 µg
|
$185.00
|
|
MRNA 34-100 |
Unmodified Spike SARS-CoV-2 mRNA 100 µg
|
$351.00
|
|
MRNA 34-1000 |
Unmodified Spike SARS-CoV-2 mRNA 1 mg
|
$1,887.00
|
|
MRNA43-20 |
Spike SARS-CoV-2 mRNA (N1-mψ) 20 µg
|
$206.00
|
|
MRNA43-100 |
Spike SARS-CoV-2 mRNA (N1-mψ) 100 µg
|
$436.00
|
|
MRNA43-1000 |
Spike SARS-CoV-2 mRNA (N1-mψ) 1 mg
|
$2,244.00
|
|
Citation database
NAME | MOLECULE VECTOR | PRODUCT | REFERENCE | |
all cells | 0 | Spike SARS CoV-2 mRNA | Bakos T. bioRxiv. 2024 doi.org/10.1101/2024.01.12.575122 |
Related products