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KLF4 mRNAs have been designed to produce high expression level of KLF4 protein.
OZB mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end.
Sequences have been optimized to yield improved stability and performance. KLF4 mRNA #MRNA80 does not bear any additional nucleotide modifications while #MRNA81 is modified with 5-methoxyuridine (5moU), #MRNA82 is modified with N1-methyl-pseudouridine to reduce innate immune response.
Molecular weights:
Quality Control:
Items | Specification | Standard QC | Superior Grade QC* |
---|---|---|---|
Appearance | Clear | ✓ | ✓ |
Integrity | Agarose gel mobility and fragment analyzer | ✓ | ✓ |
Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
A260/280 |
>1.8 for Unmodified mRNAs >1.7 for chemically modified mRNAs |
✓ | ✓ |
Sterility | Absence of bacterial growth at 37°C | ✓ | ✓ |
Endotoxin | <0.5 EU/mL | ✓ | |
dsRNA | <0.5% | ✓ | |
Fonctionality | protein expression after transfection | ✓ |
* Our catalogue mRNAs undergo the standard QC. Superior Grade QC can be performed as an additional prestation. Contact us to get a quote.
mRNA length: 1760 nt.
Storage: mRNAs must be stored at -80°C.
We recommend to aliquot the mRNA solution for a better storage.
Kit contents:
Catalog number | Unit Size | Price excl tax | Quantity / Buy |
MRNA80-20 |
KLF4 mRNA unmodified - 20 µg
|
$176.00
|
|
MRNA80-100 |
KLF4 mRNA unmodified - 100 µg
|
$282.00
|
|
MRNA80-1000 |
KLF4 mRNA unmodified - 1mg
|
$1,556.00
|
|
MRNA81-20 |
KLF4 mRNA 5moU - 20µg
|
$184.00
|
|
MRNA81-100 |
KLF4 mRNA 5moU - 100µg
|
$350.00
|
|
MRNA81-1000 |
KLF4 mRNA 5moU - 1mg
|
$1,878.00
|
|
MRNA82-20 |
KLF4 mRNA N1-mψ - 20 µg
|
$206.00
|
|
MRNA82-100 |
KLF4 mRNA N1-mψ - 100 µg
|
$372.00
|
|
MRNA82-1000 |
KLF4 mRNA N1-mψ - 1mg
|
$1,901.00
|
|
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