In vivo DogtorMag
In vivo DogtorMag™ Transfection Reagent has been designed for in vivo targeted transfection of various types of nucleic acids such as DNA, RNA, oligonucleotides using magnetic nanoparticles coated with synthetic lipids (In vivo DogtorMag). DNA complexes can be easily administrated through various injection routes such as systemic administration (intravenous, intra-artery) or local administration (intratumoral, intracerebroventricular).
In vivo Magnetofection™ main advantages in comparison to other procedures:
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Increased transfection efficiency
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Targeted process (magnetically-driven)
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Reduction of the systemic dissemination of vectors during injection
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Reduction of the vector doses
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Work under non permissive conditions (hypothermia, physiological flow conditions)
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Penetration of the vector into tissues
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Minimized toxicity
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Universal – suitable for all nucleic acids
In vivo DogtorMag kit contains In vivo Dogtor transfection reagent + In vivo CombiMag transfection reagent
Storage: In vivo Dogtor -20°C / In vivo CombiMag + 4°C
Shipping conditions: Room temperature
- NB: This reagent needs to be used with a magnet.
| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| IV-TK30220 |
Trial kit: 2 x 100 µL reagents + 1 cylinder magnet
|
$175.00
|
|
| IV-KC30220 |
Starting kit: 2 x 500 µL reagents + Magnets set
|
$531.00
|
|
| IV-DM30500 |
500 µL
|
$440.00
|
|
| IV-DM31000 |
1 mL
|
$788.00
|
|
IV-TK30220
Trial kit: 2 x 100 µL reagents + 1 cylinder magnet
$175.00
IV-KC30220
Starting kit: 2 x 500 µL reagents + Magnets set
$531.00
IV-DM30500
500 µL
$440.00
IV-DM31000
1 mL
$788.00
Citation database
| NAME | MOLECULE VECTOR | PRODUCT | REFERENCE | |
| Fibroblasts | DNA | in vivo DogtorMag | Leal AF. Method and Clin Dev. 2023 https://doi.org/10.1016/j.omtm.2023.101153 | |
| in vivo : superficial temporal vein | DNA | in vivo DogtorMag | Leal AF. Method and Clin Dev. 2023 https://doi.org/10.1016/j.omtm.2023.101153 | |
| in vivo : intravenous injection | DNA | in vivo DogtorMag | Park H. Biomaterials 2021. Volume 281 February 2022 121327 | |
| in vivo : inguinal adipose tissue | mRNA | in vivo DogtorMag | Hoang AC. Research Sqaure 2021. DOI: 10.21203/rs.3.rs-988599/v1 | |
| in vivo : inguinal adipose tissue | mRNA | in vivo DogtorMag | Hoang AC. Thesis 2022 - Univ Uulm | |
| in vivo: Lung | DNA | in vivo DogtorMag | Ungureanu BS. J Gastrointestin Liver Dis. 2016 Sep;25(3):375-83. |
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