BLOG > mRNA & LNP > Introduction to our new c-Myc messenger RNA for enhanced cellular research
Summary:
2 - Advantages of our c-Myc messenger RNA.
4 - Conclusion: The Future of Cellular Research with c-Myc messenger RNA.
We are thrilled to introduce our latest product: c-Myc mRNA, designed to enhance your cellular research. With a concentration of 1.0 mg/mL in 1 mM sodium citrate, this ready-to-use messenger RNA offers a convenient and effective solution for boosting c-Myc protein expression.
1 - Understanding c-Myc mRNA.
What is c-Myc mRNA?
C-Myc mRNA is stabilized and ready-to-use messenger RNA designed to produce high levels of c-Myc protein in cells. With a length of 1584 nt and a concentration of 1.0 mg/mL, this mRNA is optimized for cellular research. It features a 5' end cap (Cap1) and a poly(A) tail at the 3' end.
We offer three variations:
- MRNA58: 512800 g/mol.
- MRNA59: 518800 g/mol, modified with 5-methoxyuridine, 5moU.
- MRNA60: 515800 g/mol, modified with N1-methyl-pseudouridine to reduce innate immune response.
Importance of c-Myc mRNA in cellular research.
The c-Myc protein plays a crucial role in cell cycle progression, apoptosis, and cellular transformation. It is also involved in gene expression regulation and is frequently amplified in many human cancers, making it a target of interest for cancer research. C-Myc forms a heterodimer with the related transcription factor MAX, binding to the E box DNA consensus sequence and regulating the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers, and translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients.
2 - Advantages of our c-Myc messenger RNA.
Enhanced transfection efficiency with c-Myc mRNA.
Thanks to its optimized design and specific modifications, our c-Myc messenger RNA offers increased transfection efficiency, allowing robust and stable expression of c-Myc protein in cells.
Diverse applications in cellular research with c-Myc mRNA.
C-Myc messenger RNA has various applications in cellular research, including studying signaling pathways, gene expression regulation, and disease modeling. Its use can help better understand disease mechanisms and develop new therapeutic strategies.
3 - Usage and Protocols.
Optimal transfection methods for c-Myc mRNA.
For efficient transfection of c-Myc messenger RNA, we recommend using our RmesFect™ (#RM21000) and RmesFect™ Stem (#RS31000) specially designed to ensure effective delivery of messenger RNA into target cells.
Tips for maximizing results with our c-Myc mRNA.
To achieve optimal results with our c-Myc messenger RNA, it is recommended to follow the recommended transfection protocols and optimize experimental conditions based on your specific cellular system.
4 - Conclusion.
In summary, our new c-Myc messenger RNA offers an efficient and convenient solution for boosting c-Myc protein expression in cells, opening up new avenues for cellular research and drug discovery.
We invite you to explore our c-Myc messenger RNA and discover how it can contribute to your cellular research.
If you have any questions, please do not hesitate to contact us at contact@ozbiosciences.com.
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