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New Publication : Magnetic bead purification of enveloped alphavirus

 

Authors: Bianca Galasso et al.

Source: Science Direct Volume 8, 2021, 101549, ISSN 2215-0161

We are thrilled to share insights from a study entitled "Magnetic bead purification of enveloped alphavirus and flavivirus" published in Science Direct by Bianca Galasso et al.

"Virus production is an essential part of virology. The quality of virus preparation, in terms of purification and yield, can affect the outcome of experiments. Purified virus is critical for assays, as contamination from cell culture supernatants may affect results. Purified virus is also needed for vaccine preparations. The traditional process of gradient purification of virus is time consuming, with multiple steps spanning over days, and produces significant amounts of biohazard waste. Developing a more efficient alternative that provides a purified virus product is highly desirable. In this study, we performed magnetic bead purification of Zika virus (ZIKV) and Mayaro virus (MAYV) with the Mag4C-LV kit from OZ Biosciences. Currently, this kit is only indicated for use with lentiviruses and retroviruses. We found that we were able to successfully concentrate and purify both ZIKV and MAYV using the kit. Therefore, we concluded that the Mag4C-LV kit provides a quick and simple alternative to traditional virus purification methods."

Congratulations to all authors for this great article.

Read the article See our Mag4C-LV

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