TP53 mRNA
TP53 mRNA (mRNA encoding the human tumour protein 53) has been designed to produce high expression level of TP53 protein.
mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
TP53 mRNAs are also available capped with ExploCap™ upon request.
TP53 mRNA catalog number:
- #MRNA121 does not bear any additional nucleotide modifications.
- #MRNA122 is modified with 5-methoxyuridine (5moU).
- #MRNA123 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.
Quality Control:
| Items | Specification | Standard QC | Superior Grade QC* |
|---|---|---|---|
| Integrity | Agarose gel mobility and HPLC | ✓ | ✓ |
| Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
| A260/280 |
>1.8 for Unmodified mRNAs, >1.7 for chemically modified mRNAs |
✓ | ✓ |
| Sterility | Absence of growth at 37°C | ✓ | ✓ |
| Endotoxin | <0.5 EU/mL | ✓ | |
| dsRNA | <0.5% | ✓ |
*Our catalogue mRNAs undergo the standard QC. Superior Grade QC can be performed as an additional prestation. Contact us to get a quote.
Size: 20 µg, 100µg or 1 mg.
For bulk, please contact us: order@ozbiosciences.com
mRNA length: 1403 nucleotides
Storage: -80°C
Shipping : Dry ice (fee included in shipping cost)
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| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA121-20 |
TP53 mRNA Unmodified – 20 µg
|
$176.00
|
|
| MRNA121-100 |
TP53 mRNA Unmodified – 100 µg
|
$282.00
|
|
| MRNA121-1000 |
TP53 mRNA Unmodified – 1mg
|
$1,556.00
|
|
| MRNA122-20 |
TP53 mRNA 5moU - 20 µg
|
$184.00
|
|
| MRNA122-100 |
TP53 mRNA 5moU - 100 µg
|
$350.00
|
|
| MRNA122-1000 |
TP53 mRNA 5moU - 1mg
|
$1,878.00
|
|
| MRNA123-20 |
TP53 mRNA N1-mψ - 20 µg
|
$206.00
|
|
| MRNA123-100 |
TP53 mRNA N1-mψ - 100 µg
|
$372.00
|
|
| MRNA123-1000 |
TP53 mRNA N1-mψ - 1mg
|
$1,901.00
|
|
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