NanOZ Fluorescent-LNP

Lipid nanoparticles (LNPs) represent one of the most effective and safe delivery systems for the translational success of nucleic acid drugs. LNPs are spherical lipid vesicles formed by a combination of four main components: an ionizable cationic lipid, a helper phospholipid, cholesterol & a pegylated lipid, each having distinct functions. LNPs not only protect RNA from degradation, but also facilitate intracellular uptake and thus potentiate its efficacy.

At OZ Biosciences, we have developed fluorescently labeled LNPs (called NanOZ Fluo LNPs) by incorporating lipophilic dyes into their structure. These labeled LNPs enable effective monitoring of cellular internalization, intracellular trafficking, and in vivo biodistribution. Our NanOZ Fluo LNPs are ready-to-use, reliable tools designed to visualize and track LNP behavior in vitro and in vivo.

Figure: Schematic representation of fluorescent LNPs.