PD-L1 mRNA
PD-L1 mRNA (mRNA encoding encoding human programmed cell death 1 ligand 1 isoform a) has been designed to produce high expression level of PD-L1 protein.
mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
PD-L1 mRNAs are also available capped with ExploCap™ upon request.
PD-L1 mRNA catalog number:
- #MRNA124 does not bear any additional nucleotide modifications.
- #MRNA125 is modified with 5-methoxyuridine (5moU).
- #MRNA126 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.
Quality Control:
| Items | Specification | Standard QC | Superior Grade QC* |
|---|---|---|---|
| Integrity | Agarose gel mobility and HPLC | ✓ | ✓ |
| Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
| A260/280 |
>1.8 for Unmodified mRNAs, >1.7 for chemically modified mRNAs |
✓ | ✓ |
| Sterility | Absence of growth at 37°C | ✓ | ✓ |
| Endotoxin | <0.5 EU/mL | ✓ | |
| dsRNA | <0.5% | ✓ |
*Our catalogue mRNAs undergo the standard QC. Superior Grade QC can be performed as an additional prestation. Contact us to get a quote.
Size: 20 µg, 100µg or 1 mg.
For bulk, please contact us: order@ozbiosciences.com
mRNA length: 1094 nucleotides
Storage: -80°C
Shipping : Dry ice (fee included in shipping cost)
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| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA124-20 |
PD-L1 mRNA Unmodified - 20 µg
|
$176.00
|
|
| MRNA124-100 |
PD-L1 mRNA Unmodified - 100 µg
|
$282.00
|
|
| MRNA124-1000 |
PD-L1 mRNA Unmodified - 1mg
|
$1,556.00
|
|
| MRNA125-20 |
PD-L1 mRNA 5moU - 20 µg
|
$184.00
|
|
| MRNA125-100 |
PD-L1 mRNA 5moU - 100 µg
|
$350.00
|
|
| MRNA125-1000 |
PD-L1 mRNA 5moU - 1mg
|
$1,878.00
|
|
| MRNA126-20 |
PD-L1 mRNA N1-mψ - 20 µg
|
$206.00
|
|
| MRNA126-100 |
PD-L1 mRNA N1-mψ - 100 µg
|
$372.00
|
|
| MRNA126-1000 |
PD-L1 mRNA N1-mψ - 1mg
|
$1,901.00
|
|
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