Cas13d mRNA
Cas13 mRNA has been designed to produce high expression level of class 2 type VI-D CRISPR-Cas13d system derived from Ruminococcus flavefaciens XPD3002, a recently discovered RNA-guided RNA endonuclease.
OZ Biosciences mRNAs are produced by in vitro transcription and stabilized at the 5’ end by modified nucleotides capping (Cap1). These mature mRNAs contain a poly(A) tail at the 3’ end and are also optimized to yield improved stability and performance.
Cas13 mRNAs:
- #MRNA27 does not bear any additional nucleotide modifications.
- #MRNA28 is modified with 5-methoxyuridine (5moU) to reduce innate immune responses.
- #MRNA29 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.
Quality Control
| Items | Specification | Standard QC | Superior Grade QC* |
|---|---|---|---|
| Appearance | Clear | ✓ | ✓ |
| Integrity | One peak, right size | ✓ | ✓ |
| One peak, right size | ✓ | ✓ | |
| Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
| A260/280 | >1.8 for Unmod, >1.7 for modified | ✓ | ✓ |
| Sterility | Absence of growth after 14 days | ✓ | ✓ |
| Endotoxin | <0.5 EU/mL | ✓ | |
| dsRNA | <0.5% | ✓ | |
| Fonctionality | protein expression after transfection | ✓ |
* Contact us to get a quote.
Size: 20 µg, 100µg and 1 mg
For bulk, please contact us: order@ozbiosciences.com
Storage: -80°C
Shipping : Dry ice (fee included in shipping cost)
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| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA27-20 |
Cas13d mRNA 20 µg
|
$176.00
|
|
| MRNA27-100 |
Cas13d mRNA 100 µg
|
$282.00
|
|
| MRNA27-1000 |
Cas13d mRNA 1 mg
|
$1,556.00
|
|
| MRNA28-20 |
Cas13d mRNA (5moU) 20 µg
|
$184.00
|
|
| MRNA28-100 |
Cas13d mRNA (5moU) 100 µg
|
$350.00
|
|
| MRNA28-1000 |
Cas13d mRNA (5moU) 1 mg
|
$1,878.00
|
|
| MRNA29-20 |
Cas13d mRNA (N1-mψ) 20 µg
|
$206.00
|
|
| MRNA29-100 |
Cas13d mRNA (N1-mψ) 100 µg
|
$372.00
|
|
| MRNA29-1000 |
Cas13d mRNA (N1-mψ) 1mg
|
$1,901.00
|
|
MRNA27-20
Cas13d mRNA 20 µg
$176.00
MRNA27-100
Cas13d mRNA 100 µg
$282.00
MRNA27-1000
Cas13d mRNA 1 mg
$1,556.00
MRNA28-20
Cas13d mRNA (5moU) 20 µg
$184.00
MRNA28-100
Cas13d mRNA (5moU) 100 µg
$350.00
MRNA28-1000
Cas13d mRNA (5moU) 1 mg
$1,878.00
MRNA29-20
Cas13d mRNA (N1-mψ) 20 µg
$206.00
MRNA29-100
Cas13d mRNA (N1-mψ) 100 µg
$372.00
MRNA29-1000
Cas13d mRNA (N1-mψ) 1mg
$1,901.00
Citation database
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