In vivo PolyMag
In vivo PolyMag™ Transfection Reagent has been designed for in vivo targeted transfection of various types of nucleic acids such as DNA, RNA, oligonucleotides using magnetic nanoparticles coated with specific polymers.
DNA complexes can be easily administrated through various injection routes such as systemic administration (intravenous, intra-artery) or local administration (intratumoral, intracerebroventricular).
In vivo Magnetofection™ main advantages in comparison to other procedures:
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Increased transfection efficiency
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Targeted process (magnetically-driven)
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Reduction of the systemic dissemination of vectors during injection
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Reduction of the vector doses
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Work under non permissive conditions (hypothermia, physiological flow conditions)
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Penetration of the vector into tissues
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Minimized toxicity
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Universal – suitable for all nucleic acids
Sizes:
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500 µL
-
1000 µL
Storage: +4°C
Shipping Conditions: Room temperature
- NB: This reagent needs to be used with a magnet
| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| IV-TK30210 |
Trial kit: 100 µL reagent + 1 cylinder magnet
|
$175.00
|
|
| IV-KC30210 |
Starting kit: 500 µL reagent + Magnets set
|
$531.00
|
|
| IV-PN30500 |
500 µL
|
$440.00
|
|
| IV-PN31000 |
1 mL
|
$788.00
|
|
IV-TK30210
Trial kit: 100 µL reagent + 1 cylinder magnet
$175.00
IV-KC30210
Starting kit: 500 µL reagent + Magnets set
$531.00
IV-PN30500
500 µL
$440.00
IV-PN31000
1 mL
$788.00
Citation database
| NAME | MOLECULE VECTOR | PRODUCT | REFERENCE | |
| BHK-21 | SF Virus | in vivo PolyMag | Kurena B. J Virol Methods. 2017 Mar 14. pii: S0166-0934(17)30089-7. | |
| Fibrosarcoma | DNA | in vivo PolyMag | Huttinger C. J Gene Med. 2008; 10(6):655-67. | |
| Fibrosarcoma | DNA | in vivo PolyMag | Jahnke A. J Vet Med. 2007; 54():599-606. | |
| in vivo: intramuscular injection | DNA | in vivo PolyMag | Brenner TK. Eur Cell Mater. 2021 Mar 3;41:245-268. | |
| in vivo: Fibrosarcoma | DNA | in vivo PolyMag | Huttinger C. J Gene Med. 2008; 10(6):655-67. | |
| in vivo: Fibrosarcoma | DNA | in vivo PolyMag | Jahnke A. J Vet Med. 2007; 54():599-606. | |
| in vivo: left adductor muscle | siRNA | In vivo PolyMag | Ohashi K. J Biol Chem. 2014 Apr 6. | |
| in vivo: Peri anal region | DNA | in vivo PolyMag | Singh J. Am J Physiol Gastrointest Liver Physiol. 2017 Oct 19:ajpgi.00233.2017. | |
| left adductor muscle | siRNA | In vivo PolyMag | Ohashi K. J Biol Chem. 2014 Apr 6. | |
| TS/A | SF Virus | in vivo PolyMag | Kurena B. J Virol Methods. 2017 Mar 14. pii: S0166-0934(17)30089-7. |
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