BLOG > mRNA & LNP > New enzyme for low dsRNA in our mRNAs!
We improved our mRNA quality:
As part of our continuous quality improvement, we have selected a new generation of RNA polymerase that reduces dsRNA during IVT.
We are able to reduce the amount of dsRNA in our catalog and in our customized mRNAs by up to 88%.
Our new quality control limit is 0.05% of dsRNA.
Figure 1: Comparison of dsRNA amount in different mRNA produced by OZ Biosciences before and after the production process improvement.
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