F-Luc mRNA
F-Luc mRNA has been designed to produce high expression level of FireFly Luciferase. It is commonly used in mammalian cell culture to measure both gene expression and cell viability. It emits bioluminescence in the presence of the substrate, luciferin.
OZ Biosciences mRNAs are produced by in vitro transcription and stabilized at the 5’ end by modified nucleotides capping (Cap1). These mature mRNAs contain a poly(A) tail at the 3’ end and are also optimized to yield improved stability and performance.
Fluc mRNAs are also available capped with ExploCap™.
F-Luc mRNA Catalog Number:
- #MRNA16 does not bear any additional nucleotide modifications.
- #MRNA12 is modified with 5-methoxyuridine (5moU) to reduce innate immune response.
- #MRNA24 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.
- #MRNA12c and #MRNA16c are labelled with Cy5 (Sulfo-Cyanine5) by replacing 15% of U or moU by UTP-Cy5.
Quality Control
| Items | Specification | Standard QC | Superior Grade QC* |
|---|---|---|---|
| Appearance | Clear | ✓ | ✓ |
| Integrity | Agarose gel mobility and fragment analyzer | ✓ | ✓ |
| Concentration | 1mg/ml +/- 5% | ✓ | ✓ |
| A260/280 | >1.8 for Unmod, >1.7 for modified | ✓ | ✓ |
| Sterility | Absence of growth | ✓ | ✓ |
| Endotoxin | <0.5 EU/mL | ✓ | |
| dsRNA | <0.5% | ✓ | |
| Functionality | protein expression after transfection | ✓ | ✓ |
*Our catalogue mRNAs undergo the standard QC. Superior Grade QC can be performed as an additional prestation. Contact us to get a quote.
We recommend using our transfection reagents RmesFect or RmesFect Stem in order to reach high transfection efficiency and optimum protein expression level.
Fluc mRNA length: 1872 nt
Size: 20 µg, 100µg and 1 mg
Storage: -80°C
Shipping : Dry ice (fee included in shipping cost)
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For bulk, please contact us: order@ozbiosciences.com
| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA16-20 |
F-Luc mRNA 20 µg
|
$176.00
|
|
| MRNA16-100 |
F-Luc mRNA 100 µg
|
$282.00
|
|
| MRNA16-1000 |
F-Luc mRNA 1mg
|
$1,556.00
|
|
| MRNA12-20 |
F-Luc mRNA (5moU) 20 µg
|
$184.00
|
|
| MRNA12-100 |
F-Luc mRNA (5moU) 100 µg
|
$350.00
|
|
| MRNA12-1000 |
F-Luc mRNA (5moU) 1mg
|
$1,878.00
|
|
| MRNA24-20 |
F-Luc mRNA (N1-mψ) 20 µg
|
$206.00
|
|
| MRNA24-100 |
F-Luc mRNA (N1-mψ) 100 µg
|
$372.00
|
|
| MRNA24-1000 |
F-Luc mRNA (N1-mψ) 1 mg
|
$1,901.00
|
|
Citation database
| NAME | MOLECULE VECTOR | PRODUCT | REFERENCE | |
| all cells | 0 | F-Luc mRNA | Terai K. Biomed Pharmacother. 2026 Jan:194:118920. | |
| all cells | 0 | F-Luc mRNA | Kopilovic B. Mat Today Bio 2025. vol(33)-101975 | |
| all cells | 0 | F-Luc mRNA | Kopilovic B. Materials Today Bio 2025. (42)doi.org/10.2139/ssrn.5154242 | |
| all cells | 0 | F-Luc mRNA | Ngalle Loth A. J Control Release . 2025 Jan 9:379:164-176. | |
| all cells | 0 | F-Luc mRNA | Oba R. Polym Adv Tech 2024 vol 35 - 12 | |
| all cells | 0 | F-Luc mRNA | Hassanel DNBP. Int J Pharm. 2024 Sep 15:665:124695. | |
| all cells | 0 | F-Luc mRNA | Tai JA Vaccines (Basel). 2024 Jul 9;12(7):757. | |
| all cells | 0 | F-Luc mRNA | Kranse O. Thesis (U. Cambridge) 2024 | |
| all cells | 0 | F-Luc mRNA | Camperi J. Anal Chem. 2024 Feb 20. doi: 10.1021/acs.analchem.3c05539 | |
| all cells | 0 | F-Luc mRNA | Medjmedj A. Nanomaterials 2022 12(14) 2446 | |
| all cells | 0 | F-Luc mRNA | Kranse O. G3 (Bethesda). 2021 Feb 9;11(2):jkaa058 |
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