HA(FL)-H1N1 saRNA
Ready-to-use stabilized HA(FL)-H1N1 saRNA
HA(FL)-H1N1 saRNAs have been designed to produce high expression level of HA(FL)-H1N1 protein with enhanced length of duration. saRNAs are produced by in vitro transcription. saRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
HA(FL)-H1N1 saRNAs are also available capped with ExploCap™ upon request.
saRNA has been constructed based on replicons of positive-sense ((+)-RNA) viruses (Venezuelan equine encephalitis Virus (VEEV)), where the coding sequence of the viral structural proteins is replaced with that of a gene of interest (GOI, here HA(FL)-H1N1), while retaining the coding sequences of non-structural proteins (nsPs), including the viral RNA-dependent RNA polymerase. Please note that OZ Biosciences saRNAs encodes also for Puromycin Resistance Cassette, which does not alter the expression of the GOI but can be used for cell selection.
- #MRNA76 does not bear any additional nucleotide modifications.
- #MRNA77 is modified with 5-methyl-Cytidine (m5C) (100% replacement of Cytidine).
mRNA length: 10774 nt
Size: 20µg, 100µg and 1mg
Storage: saRNAs must be stored at -80°C. We recommend to aliquot the RNA solution for a better storage and avoid freeze/thaw cycles.
For Bulk, please contact us : order@ozbiosciences.com
| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA76-20 |
20µg (unmodified)
|
$120.00
|
|
| MRNA76-100 |
100µg (unmodified)
|
$375.00
|
|
| MRNA76-1000 |
1mg (unmodified)
|
$1,975.00
|
|
| MRNA77-20 |
20µg (m5C)
|
$170.00
|
|
| MRNA77-100 |
100µg (m5C)
|
$400.00
|
|
| MRNA77-1000 |
1mg (m5C)
|
$2,075.00
|
|
Citation database
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