BLOG > Publications & Citations > An mRNA-encoded scFv antibody targeting the helix-α3 of HPV18 E7 oncoprotein
Authors: Feng Han et al.
Source: mBio 0:e02627-25.
We're delighted to share insights from a recent study entitled "An mRNA-encoded scFv antibody targeting the helix-α3 of HPV18 E7 oncoprotein as a novel antiviral strategy" published in mBio by Feng Han et al.
Congratulations to all the authors on this excellent article!
They identified a novel antiviral target on the HPV18 E7 oncoprotein and demonstrated that delivering antibody-encoding mRNA can effectively neutralize viral proteins and suppress tumor growth in vivo.
Our Ab-DeliverIN was used to transfect fluorescently labeled antibodies into HeLa cells, enabling the researchers to validate intracellular delivery and assess the inhibitory effects of these antibodies on cell proliferation.
Read the article See Ab-DeliverIN
Related publications
17,18-epoxyeicosatetraenoic acid ameliorates mRNA-LNP–induced local inflammation
Aurora Kinase A inhibition favors CRISPR/Cas9 gene correction over knock-out
