FLuc saRNA
FLuc self-amplifying RNAs have been designed to produce high expression level of Firefly Luciferase protein with enhanced length of duration.
FLuc saRNAs are produced by in vitro transcription. saRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance.
FLuc saRNAs are also available capped with ExploCap™ upon request.
FLuc self-amplifying RNA has been constructed based on replicons of positive-sense ((+)-RNA) viruses (Venezuelan equine encephalitis Virus (VEEV)), where the coding sequence of the viral structural proteins is replaced with that of a gene of interest (GOI, here FLUC), while retaining the coding sequences of non-structural proteins (NsPs), including the viral RNA-dependent RNA polymerase.
Please note that saRNAs encodes also for Puromycin Resistance Cassette, which does not alter the expression of the GOI but can be used for cell selection.
- #MRNA72 does not bear any additional nucleotide modifications.
- #MRNA73 is modified with 5-methyl-Cytidine (m5C) (100% replacement of Cytidine).
mRNA length: 10741nt.
Size: 20µg, 100µg and 1mg
Storage: saRNAs must be stored at -80°C. We recommend to aliquot the RNA solution for a better storage and avoid freeze/thaw cycles.
For bulk, please contact us: order@ozbiosciences.com
| Catalog number | Unit Size | Price excl tax | Quantity / Buy |
| MRNA72-20 |
FLuc saRNA 20µg (unmodified)
|
$120.00
|
|
| MRNA72-100 |
FLuc saRNA 100µg (unmodified)
|
$375.00
|
|
| MRNA73-20 |
FLuc saRNA 20µg (m5C)
|
$170.00
|
|
| MRNA72-1000 |
FLuc saRNA 1mg (unmodified)
|
$1,975.00
|
|
| MRNA73-100 |
FLuc saRNA 100µg (m5C)
|
$400.00
|
|
| MRNA73-1000 |
FLuc saRNA 1mg (m5C)
|
$2,075.00
|
|
Citation database
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